Celiac Disease

What is the progression of celiac disease and related disorders?

  1. As children, we consume mucus forming foods (and even as a fetus) and due to mucus build-up inside the intestines, candida albicans yeast fungus grows out of control.  (Wheat, barley, rye, corn and milk are the five (5) most mucus forming foods.)  Normally good bacteria keeps candida level to less than 1% of the total intestinal bacteria level.  However, when the mucosal lining thickens due to mucus forming foods, the good bacteria cannot penetrate the thick mucus to "feed on" the candida, to keep it in check, so it grows out of control (infection).    

  2. As the candida yeast fungus multiplies, candida roots, called rhizoids, grow through the intestinal walls.  Candida roots die off regularly, and new ones grow.  When the old ones die off, they leave small holes in the intestine.  This is commonly called "leaky gut".  

http://www.ehow.com/facts_6165434_rhizoids-leaky-gut-syndrome.html

http://www.common-sense-health.com/candida

http://www.how-to-boost-your-immune-system.com/systemic-candida.html

http://www.ninazu.com/whatis.html

http://www.candida-yeast-explained.com/leaky-gut-and-candida.html       

http://www.lef.org/protocols/infections/fungal_infections_candida_01.htm

http://www.glutensensitivity.net/VojdaniDiagrams.htm

   a.      Note:  Stomach ulcers and intestinal ulcers can also allow proteins to enter the bloodstream. 

  1. Leaky gut allows proteins and other undigested food, including gluten, to enter the bloodstream.  

  2. All autoimmune responses are due to proteins entering the bloodstream.  

A.    Proteins entering the bloodstream can cause toxicity (see  http://en.wikipedia.org/wiki/Gluten_sensitivity).   Proteins entering the bloodstream can also cause an innate immune response, (see http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1954879/).

1)    NOTE:  Other proteins which enter the bloodstream ALSO cause toxicity and an innate immune response directed to those particular proteins.   (The medical community has not yet identified all of the other toxicities related to all of the other proteins.)   

B.    The proteins that leak into the blood cause our bodies to have "normal" autoimmune reactions, which is to produce antibodies.  Our body correctly produces antibodies to take care of the foreign proteins (kill/breakdown/surround with mucus for elimination). 

1)    NOTE:  If a person stops consuming any one particular protein, that particular protein will no longer be leaking into the bloodstream.  Therefore, their body should stop making autoimmune antibodies against that particular protein. 

  1. Proteins which enter the bloodstream cause an array of other health complications, i.e. acidosis, liver diseases, other food allergies/sensitivities, etc.    

    1. The these foreign proteins, such as the proteins in cereal grains, enter the bloodstream, and are free to travel throughout the body before the protein is destroyed by our antibodies. 

    2. The point at which the protein is destroyed by our antibodies, it becomes surrounded with mucus, which is our normal body’s response to foreign particles to protect healthy cells from touching the foreign protein and so that our body can eliminate the “waste”. 

    3. Since proteins from wheat, barley and rye are so gluey, the mucus that surrounds the protein is thicker than normal and the protein-mucus particle adheres to healthy body cells wherever it is at.  It does not get eliminated from the body easily. 

  1. Gluten type substances are found in all cereal grains, however wheat, barley and rye are the most glue-type, mucus forming, substances that people, as well as animals, eat.  It is believed that this is the reason so many people concentrate on wheat, barley and rye -free diets, rather than just staying away from all glue-like (gluten) cereal grains.    

  2. All mucus forming foods causes mucus build-up, discomfort, and dis-ease of the celiac area of the body (celiac plexus). 

    Mucus build-up, which leads to candida overgrowth, which leads to leaky gut, is the cause of most all autoimmune diseases.  

The cause of celiac disease is that simple.

 

What is the treatment for leaky gut, candida overgrowth and mucus build-up?

    Stop, or cut way back, on eating the heavy, sticky mucus forming foods, particularly wheat, barley, rye, corn and milk.  Totally eliminating these for many months allows the body to cleanse itself more easily and more thoroughly. 

    Cleanse out the mucus-protein buildup and the candida that lives in the mucus, from all parts of the body, so that leaky intestines can heal (so the holes can close back up).  This is not easy.  Numerous websites discuss ridding oneself of candida overgrowth by eating candida eliminating diets and taking supplements, however very few discuss ridding oneself of mucus build-up throughout the body, joints and organs at the same time one is cleansing the candida out of the body.  Eliminating mucus forming foods and eating more raw foods and eating less grains usually works well.  Consuming Fenugreek and Slippery Elm Bark tea/capsules also helps speed up the process.  Taking a Guaifenesin/Phenylephrine HCL drug also helps (for those who are willing to take drugs).  Betaine HCL also has been found to speed up mucus cleansing.  

    Once the mucus is back to normal levels and the candida is no longer growing out of control, the intestines will heal and proteins (and other undigested foods) will no longer leak into the bloodstream.  

    Once healed, keep your diet low in mucus forming foods so that candida does grow out of control again and cause leaky gut again. 

  Regarding candida diets found on the internet, they all are fairly close to one another and are all pretty good.  One thing not mentioned much is "the amount" of carbohydrates/sugars consumed each day.  If carbs are limited to 50 per meal (150 per day), then it doesn't really matter what kind of food they come from.  Cutting out the "sweet" fruits is not really necessary if you limit your overall daily carb intake to 150.  Some people go as low as 50 carbs per day.  

    Keeping the body alkaline is also important in killing candida, and cleansing mucus.  Apple cider vinegar, lemons and limes are the three of the most alkaline foods.  Drinking 8-10 tablespoons of raw apple cider vinegar (with water) every day makes the body alkaline, and stops candida from multiplying.  Adding 1-2 cups of vinegar to bathwater (the less expensive kind without mother strands is OK) also alkalizes the body, and rids the skin of candida, and therefore allows our largest elimination organ to work properly again.  Moisturizing the skin with coconut oil also keeps candida from overgrowing on the skin.   

    Also, it is the mucus and candida that destroys the intestinal villi, NOT autoimmune antibodies that destroy healthy villi. The autoimmune system will not attack our body's healthy cells.  "Autoimmune diseases are characterized largely by the presence of autoantibodies. While autoantibodies were reported over a century ago, many scientists at the time were unwilling to accept the possibility that the immune system attacks its own cells. Ehrlich argued that autoimmunity was not possible and proposed the theory of horror autotoxicus to describe the body's innate aversion to immunological self-destruction by the production of autoantibodies. Now that humans are understood to be the product of multiple genomes, increasing evidence supports Ehrlich's view. When an innate immune system is forced to respond to a chronic microbiota, the resulting cascade of chemokines and cytokines will also stimulate an adaptive response. Antibodies are notoriously polyspecific, and the likelihood that antibodies generated to target metagenomic fragments will also target human proteins (target "self") is finite." http://autoimmunityresearch.org/preprints/Proal_MHB_Chapter_preprint.pdf       

    Due to candida spreading and infecting other parts of the body, those parts of the body become damaged.  "Gluten sensitivity, celiac disease (CD) and gluten-sensitive enteropathy are terms that have been used synonymously to refer to a disease process affecting the small bowel and characterized by gastrointestinal symptoms and malabsorption. However, since 1966 scientific evidence has been accumulated demonstrating that gluten sensitivity can exist even in the absence of enteropathy. For example, patients with dermatitis herpetiformis and presentation of blistering skin do not have any gastrointestinal symptoms but have elevated gliadin antibody in the blood which improves on a gluten-free diet (1). Additionally, associations of CD with the involvement of other organs such as the central and peripheral nervous systems also go as far back as 1966 (2). However, until recently, this phenomenon of immune reaction against neural tissue, in particular the cerebellum, was attributed to vitamin deficiencies.  During the past five years, based on overwhelming evidence of immune pathogenesis involving organs other than gut and skin, many scientists have begun to re-evaluate the notion that gluten sensitivity is solely a disease of the gut. Other organs suspected of involvement include: the joints (3-11), the heart (12-15), thyroid (16-18), bone (19-20), the brain cerebellum and the neuronal synapsins (14-28). Although it is believed that the prevalence of CD is one in one hundred, for every symptomatic patient with CD there are eight patients with CD with no GI symptom. In addition 10% of the healthy population have significant elevation in gliadin antibody but no obvious classic disease manifestations." 

http://www.wesupportandywakefield.com/documents/ImmunGlutSenBeyond.pdf

http://www.direct-ms.org/pdf/ImmunologyOther/Gluten%20sensitivity.pdf

    It is a common misconception that celiac disease (gluten intolerance) is possibly due to a genetic disorder.  Since there has not been any one special gene pattern in EVERY celiac patient, it is highly unlikely that genes have any connection to celiac disease.  However, the leaky gut (celiac disease) affects people of European (especially Northern European) descent more than the average.  It is believed that certain nationalities tend to retain mucus and develop leaky gut more than others.  

    Those affected are almost always infected with systemic candida albicans and have an overload of mucus in the body (in which the candida lives).  This is due to the thick, sticky, glue-like mucus that forms in the body when eating grains, particularly wheat, barley, rye and corn.  A build-up of mucus can also occur from eating dairy products, as well as eating a diet that is too acidic (having a body that is too acidic).   

    Candida, that lives in the thicker than normal mucosal lining of the intestines, will damage to the villi (shortening and villous flattening) in all regions of the intestines, including the lamina propria (Lamina propria is loose connective tissue in a mucosa.  Lamina propria supports the delicate mucosal epithelium, allows the epithelium to move freely with respect to deeper structures, and provides for immune defense.  Compared to other loose connective tissue, lamina propria is relatively cellular.  It has been called "connective tissue with lymphatic tendencies".) and crypt regions, as well as grow rhizoids (roots) through the intestinal walls, resulting in leaky gut.  http://www.siumed.edu/~dking2/erg/giguide.htm


    Because of the broad range of symptoms candida and leaky gut cause, it can be difficult to diagnose.  The symptoms can range from mild weakness, bone pain, and aphthous stomatitis to chronic diarrhea, abdominal bloating, and progressive weight loss.  If a person with the candida and leaky gut continues to ignore it, studies have shown that he or she will increase their chances of gastrointestinal cancer many times that of the normal population. Further, gastrointestinal carcinoma or lymphoma develops in many patients.  It is therefore imperative that candida and leaky gut is quickly and properly diagnosed so it can be treated as soon as possible.

http://glutenfreeworks.com/blog/2009/09/10/treating-candida-albicans-intestinal-yeast-overgrowth-in-celiac-disease/#more-454

http://www.direct-ms.org/pdf/ImmunologyOther/Gluten%20sensitivity.pdf

 

    Rheumatoid arthritis is also caused by leaky gut and candida.   "Patients with rheumatoid arthritis (RA) often feel there is an association between food intake and rheumatoid disease severity. In a recent study of this putative immunological link between gut immunity and RA, food antibodies were measured in serum and perfusion fluid from the jejunum of RA patients and healthy controls to determine the systemic and mucosal immune response. IgG, IgA and IgM antibodies to dietary antigens were measured in serum and jejunal perfusion fluid from 14 RA patients and 20 healthy subjects. The antigens originated from cow’s milk (a-lactalbumin, b- lactoglobulin, casein), cereals, hen’s egg (ovalbumin), cod fish and pork meat. In the intestinal fluid of many RA patients, all three immunoglobulin classes showed increased food specific activities, including gliadin antibodies."  

http://www.glutensensitivity.net/Vojdani_Immun_Glut_SenAug07-1.pdf

 

What you do not want to do!

    Here is something which is being developed by scientist (not nutritionist) that you would NEVER EVER want to take.  It is called NEXWAX2®.  "Nexvax2® aims to desensitise patients to the three specific peptides...."  http://www.sciencedaily.com/releases/2011/05/110509091559.htm 

    ImmusanT in collaboration with INOVA Diagnostics wants everyone to ignore the root cause of the problem by developing a vaccine to cover-up symptoms and desensitise people.  I guess we could just ignore the leaky gut root cause of the problem, and just desensitise ourselves instead.  That would be easy.  

 

 

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